Microdosing Psychedelics

Microdosing is the practice of taking a very small amount of a psychedelic for various benefits.

Microdosing will require proper measurements to ensure correct dosing of your chosen psychedelic substance. Microdosing protocols can also be useful to individuals who seek to find particular beneficial effects from microdosing. Many people find microdosing is a helpful way to prepare for and integrate larger dose journeys.

How to Microdose for Mindfulness & Wellbeing

A Practical & Evidence Based Course

Microdosing Introduction

Microdosing involves taking a small amount of a psychedelic substance on a regular or irregular basis for various benefits, such as enhanced mood, creativity, energy, awareness and connection.

Microdoses are usually between 5 and 10 percent of a standard psychedelic dose, amounts that don’t impede everyday function. While advocates argue that the practice delivers some of the cognitive and medicinal benefits of a full-dose of a psychedelic, scientific studies on microdosing are inconclusive.

Popularized in the West by Dr. James Fadiman, microdosing has become increasingly common. Although the science of microdosing is unclear, thousands of anecdotal reports and the growing popularity of microdosing indicates that microdosing works for some people. Microdosing does not come without risk however, as studies indicate that habitual microdosing may carry heart health risks. Although with slightly differing effects, any classic psychedelic substance, such as LSD and psilocybin containing mushrooms are used for microdosing. Most people use LSD or psilocybin for microdosing.

Microdosing with MDMA is dangerous and strongly discouraged.


Microdosing Effects

Primary reported effects of microdosing include improved mood, creativity and general cognition. However, effects may vary by individual.

People often believe that microdosing must be sub-perceptual, meaning the effects are not perceptible. However, this is not true. It is okay to feel, notice and perceive changes in your consciousness from a microdose.

Reported microdosing effects:

  • Increased energy

  • Mental clarity

  • Improved problem solving ability

  • Increased creative thinking

  • Improved focus

  • Positive mood

  • Facilitated emotional connection

  • Improved self-awareness

  • Improved presence

Again, anecdotal reports suggest that microdosing enhances wellbeing and cognition; however, such accounts are potentially biased and inaccurate. If you choose to proceed with microdosing, keep in mind that these effects are not guaranteed.

How to Microdose for Mindfulness & Wellbeing

A Practical & Evidence Based Course

Measuring Microdoses

Microdosing is not as simple as taking a low dose of a psychedelic substance. Proper measurement is necessary to ensure an accurate microdose.

For LSD, a microdose is anywhere between 5μg and 20μg. For mushrooms, a microdose is anywhere between 0.1g and 0.5g of powdered mushrooms.

Since the amount of psilocybin varies per mushroom and even per part of a single mushroom, blending the mushrooms into a powder ensures a more balanced distribution of psilocybin among each microdose you will take.

How to Microdose Mushrooms

You will need:

  • Psilocybin mushrooms

  • A dry container

  • A blender (optional)

  • A digital scale or measuring spoons

Step by step process:

  1. Blend or break up your mushrooms into fine powder or small bits.

  2. Store your powder in a dry container, keep the container in the dark.

  3. Use measurement spoons or a digital scale to measure your mushroom microdose. Anywhere from 0.05g to 0.5g is a proper microdose.

  4. Experiment with different doses to find what works for you. Start small.

How to Microdose LSD

You will need:

  • LSD

  • Bottle or container

  • Distilled water

  • A 10ml Pipette/syringe

Step by step process:

  1. Ensure the amount of LSD per tab. Depending on how much LSD you have on your tab, the maths will vary. For this walkthrough, we will assume you have a tab containing approximately 100μg of LSD.

  2. Pour 100ml of distilled water in an airtight container or bottle.

  3. Drop your tab of 100μg in your airtight container.

  4. Close the container tightly and shake it around for a minute.

  5. Put the container in the fridge for 48 to 72 hours.

  6. After 48 to 72 hours, the LSD water is ready. Use your pipette / syringe to measure how much LSD you want to take. A 100μg tab of LSD in 100ml of water will provide about 10μg of LSD for every 10ml of water.

  7. Experiment with different doses to find what works for you. Start small.


Microdosing Protocols

Microdosing is often practiced in a routinely fashion. Various routine protocols exist, such as the Fadiman or the Stamets protocols. However you are free to design your own. Experiment.

Many people also take microdoses without following a routine, and simply take their microdose on a day that they feel like microdosing. Such practices may impede the potential long-term effects of microdosing regularly.

The Fadiman Protocol

The Fadiman protocol is the most popular and common microdosing protocol.

Psychologist and writer Dr. James Fadiman has been researching psychedelics since the 1960s. His protocol recommends taking a microdose every three days. This is a go-to protocol for beginners.

It is recommended you continue this cycle for 30 to 60 days and then reset by stopping the microdose protocol for 2 to 4 weeks (4 weeks is recommended).

Have you been following the Fadiman protocol for at least 2 weeks and want to share about your experience? You can contact us to talk about your experience.

Every Other Day Protocol

The every other day protocol is developed by the Microdosing Institute in cooperation with James Fadiman and has been proven to be more beneficial for people who microdose for medical purposes to help them ease the effects of conditions such as depression, ADHD, ADD, (social) anxiety, migraines or cluster headaches.

It is recommended you continue this cycle for 30 to 60 days and then reset by stopping the microdose protocol for 2 to 4 weeks (4 weeks is recommended).

Have you been following this protocol for at least 2 weeks and want to share about your experience? You can contact us to talk about your experience.

Two Fixed Days Protocol

A challenge of the Fadiman protocol is having continuously changing days of the week as microdosing days. Some people might benefit from a fixed day schedule, where you can choose two fixed weekdays (that are best for your own schedule) to microdose—for example Monday and Friday.

It is recommended you continue this cycle for 30 to 60 days and then reset by stopping the microdose protocol for 2 to 4 weeks (4 weeks is recommended).

Have you been following this protocol for at least a month and want to share about your experience? You can contact us to talk about your experience.


Consider booking a support call with a member of our team to explore microdosing with holistic guidance.

How to Microdose for Mindfulness & Wellbeing

A Practical & Evidence Based Course